Crash when save mean a damaged savegame. The best option is discard it and load and OLD savegame.
You can try clean the problematic savegame with ReSaver (link for SE) and try again.
But a lot of times the problem is in the skse co-save. The only cleaner for skse is NioCleaner and i not know if works in SE. Make a security copy before use it.
Original URL: https://www.loverslab.com/topic/114802-crashing-when-saving-again/?do=findComment&comment=2490890